The ReoCell cell therapy program, based on mesenchymal stem cells (MSCs), is used as an adjunct to standard treatment for type 2 diabetes. Administration of the cell product aims to reduce inflammation, improve tissue sensitivity to insulin, and support pancreatic function.
Book a consultationType 2 diabetes is a chronic condition characterized by elevated blood glucose levels caused by insulin resistance. As a result, the body's cells cannot use insulin effectively, which leads to a buildup of glucose in the blood.
Insulin is a hormone that helps glucose move from the bloodstream into cells, where it becomes a source of energy. In type 2 diabetes, cells stop responding to insulin normally. At first, the pancreas compensates by producing more of it, but over time its cells become exhausted and glucose accumulates in the blood.
Type 2 diabetes accounts for more than 90% of all diabetes cases. Unlike type 1, insulin is usually still produced, but it does not work effectively. The disease develops gradually and can go unnoticed for years.
Symptoms may develop gradually and include:
frequent urination;
persistent thirst;
numbness or tingling in the hands or feet;
slow healing of wounds, cuts, and scrapes
slow healing of wounds or infections.
increased appetite along with unexplained weight loss
blurred vision
chronic fatigue and drowsiness
“Some people have no symptoms at all, and diabetes is discovered by chance during a routine blood test. That is why screening is more important than waiting for symptoms to appear,”
Nataliia Tereshchenko
Endocrinologist, Highest Qualification Category Physician
Diagnosis is based on laboratory tests of venous blood using international criteria. Diabetes is confirmed if at least one of the following results is present:
Treatment is built step by step, from lifestyle changes to combinations of medications and, if needed, insulin. The goal is to keep glucose within the target range and prevent complications.
The regimen is selected individually by the physician based on HbA1c level, weight, heart and kidney health, and coexisting conditions.
Cell therapy with mesenchymal stem cells (MSCs) is a possible addition to standard treatment. It does not replace diet, medication, or monitoring by an endocrinologist, but works from a different angle: mesenchymal stem cells act on chronic inflammation and reduced tissue sensitivity to insulin.
The decision to use cell therapy is made individually, after an examination and consultation with an endocrinologist, with the aim of reducing potential risks of vascular complications of diabetes.
In treating Type 2 diabetes, mesenchymal stem cells (MSCs) are introduced into the patient's body, where they can act through several mechanisms:
MSCs can transform into beta cells, improving insulin production.
MSCs possess anti-inflammatory properties that help reduce overall inflammation in the body.
MSCs can enhance the sensitivity of cells to insulin, allowing the body to use glucose more effectively.
The ability of adult stem cells to convert into vascular cells and produce various endothelial growth factors promotes the formation of new blood vessels (neovascularization) in the affected limb. Stem cells create new bypass networks, circumventing areas of narrowing. This process restores blood circulation, improving the nourishment and oxygen supply to the lower limbs.
Patients who have undergone MSC therapy may experience the following positive effects:
Improved blood sugar stabilization
Reduced risk of complications
Improved immunity
Reduced need for insulin
Improved sexual function
Improved overall well-being
Reduced dosage of blood sugar medication
Reduced severity and frequency of complications
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The most consistent research data on mesenchymal stem cell therapy in type 2 diabetes concern three things: a reduction in glycated hemoglobin (HbA1c), a reduced need for insulin, and improved tissue sensitivity to insulin.
One of the main goals of therapy is to lower the medication dose. In a meta-analysis of randomized trials (Kashbour et al., Diabetology & Metabolic Syndrome, 2025) covering 13 studies and 507 patients, the daily insulin requirement in the MSC group was markedly lower than in the placebo group. In the subgroup of patients with type 2 diabetes specifically, this was one of the most pronounced effects. A separate meta-analysis focused on type 2 diabetes (Ranjbaran et al., Journal of Diabetes Investigation, 2021) reached similar conclusions: insulin doses decreased, and HbA1c levels dropped significantly.
According to the 2025 meta-analysis, glucose levels after meals decreased more consistently in patients with type 2 diabetes than fasting glucose levels. This is consistent with the idea that MSCs act primarily on tissue sensitivity to insulin.
Some studies assessed C-peptide levels, a marker of the body’s own insulin production. In the overall sample, C-peptide rose at 12 months, but in the type 2 diabetes subgroup specifically, the changes were inconsistent. In other words, restoring the function of insulin-producing cells is not yet considered a guaranteed outcome.
According to the meta-analyses, no serious adverse events or deaths were recorded during treatment and follow-up. The most common adverse reactions were mild to moderate and resolved on their own: upper respiratory tract infections, nausea, abdominal pain, and injection-site reactions. Episodes of hypoglycemia did occur, but they are linked more to concurrent insulin use than to the therapy itself. Kashbour et al. meta-analysis, 2025 (adverse event analysis across 8 studies).
Cell therapy does not target a single symptom, but several biological mechanisms at once. Its potential effect is linked to the release of biological molecules that act on the beta cells of the pancreas, reduce inflammation, and activate tissue regeneration.
The doctor reviews the medical history and examination results, assesses the patient's general condition and determines the indications for treatment.
Based on the diagnosis, a personalised treatment programme is developed that can combine standard therapy with modern regenerative methods where indicated.
All procedures are carried out in accordance with approved medical protocols under the supervision of experienced specialists.
After treatment the doctor monitors the patient's condition, analyses the indicators and adjusts further recommendations if needed.
Repeat consultations and assessment of clinical indicators are carried out to track treatment effectiveness and maintain the results achieved.
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Every patient is unique, so we develop personalised treatment plans that take into account all the features of your body. Our task is to achieve the maximum therapeutic effect for every patient.
Our doctors and scientists are recognised experts in medicine. They continuously improve their knowledge and skills, introducing the newest treatment methods.
From manufacturing cell products to using them in treatment. Our modern biotechnology laboratory and cryobank guarantee the highest quality and safety.
A complete package of permits ensuring safe and effective treatment.
Diabetes control today means fewer risks in the future
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Sincere thanks to Dr. Dmytro Andriiovych and Tetiana Vasylivna — attentive, professional, and they explain everything in detail. I also thank the anesthesiologist Oleksandr Anatoliiovych — everything went calmly and comfortably.
The clinic is very cozy, with a pleasant atmosphere. The nurses are attentive and caring and support you at every stage. The administrators are always friendly and well organized. The doctors are always in touch, which gives confidence and peace of mind.
I have only positive impressions. I really liked it and recommend it to everyone.
I had an exosome procedure for hair loss at the clinic — I saw the result after just 2 weeks. Thank you!
Incredible impressions of the clinic's specialists! Especially endocrinologist Natalia Borysivna and gynecologist Lina Aliievna! An extremely high level of professionalism! Very caring and gentle! They approach their work with enthusiasm ❤️🙏. They know how to give the patient their full attention! I highly recommend this clinic!…
A great team of professionals who treat the cause, not the symptom.
Great service. True professionals. Pleasant communication. Friendly staff. Definitely recommend 🤗…
A very high-quality, modern clinic: a thorough examination, and all the necessary tests are done on site. Tetiana Karpenko is an attentive, professional doctor. Dmytro Andriiovych is simply the best.
Thank you for the wonderful therapy, its effectiveness, the kind attitude and the atmosphere. I had fibroblast therapy to improve my facial skin. I noticed that my skin turgor improved, the pigment spots disappeared, and my skin really became more lively and attractive. Thank you :)
I want to thank the whole ReoCell clinic team for their wonderful work! I chose the autologous fibroblast procedure for natural skin renewal and have no regrets at all.
I appreciate the comprehensive approach: everything was explained to me in detail, a thorough diagnosis was carried out, and I was supported throughout the entire treatment. The material collection and the subsequent cell injection were comfortable.
The result exceeded my expectations! My skin became much fresher and firmer, and fine wrinkles decreased. The best part is the feeling of renewal from within, with nothing artificial. I am very glad I chose this particular clinic and this technology. Definitely recommend!
I am very grateful to ReoCell clinic! I used fibroblast cell therapy for skin rejuvenation; I am 55 years old. My own fibroblasts were used, and I later also banked them in the ReoCell bank. The result exceeded my expectations. My skin became smooth, fresh and firm. I recommend it!
At ReoCell clinic I had a rejuvenation procedure with a product based on fibroblast-conditioned medium to improve my skin. I was bothered by constant inflammatory breakouts, redness and dryness. I saw the result after 2 weeks — the red spots disappeared, and my skin looked "fresh" and more hydrated. After a course of 3 procedures over 3 months, my skin became firmer, the tone evened out, the dullness disappeared, and I looked healthier and more radiant. Half a year has passed since the start of treatment, and the effect still lasts; acquaintances and friends say I look rested and younger. I see the proof of these words in the mirror too, which makes me happy: in the morning light make-up is enough, and my look and mood are wonderful. Thank you to dermatologist Maryna Malanushenko for the excellent result!
Polite and professional staff
Thank you! I came to the clinic with knee osteoarthritis. It got much better: the pain went away, and according to MRI the cartilage structure improved!!! For 2 years now I have been living without knee pain and without intra-articular injections. I especially want to thank Oksana Spivakova for managing my case, monitoring and communicating with the doctors :) I recommend this therapy
Type 1 diabetes is autoimmune: the immune system destroys the pancreatic cells that produce insulin, so the body is left with almost no insulin of its own. These patients need insulin injections from the start and for life, and the disease more often begins in childhood or young adulthood.
Type 2 diabetes develops through a different mechanism: insulin is produced, but the tissues respond to it poorly. It is associated mainly with lifestyle and heredity, and it develops for a long time without any symptoms.
Remission is a state in which blood glucose stays within the normal range without glucose-lowering medication. And it is possible. In the UK’s DiRECT study, published in The Lancet, a managed weight loss program helped about half of participants achieve remission within a year, and the more weight a patient lost, the higher their chances were.
However, type 2 diabetes is a progressive disease: the insulin-producing cells of the pancreas gradually become exhausted, so treatment often has to be intensified over time. The greatest chances of remission are in the early stages and with significant, sustained weight loss.
The condition is assessed not by stages but by the degree of compensation, that is, how well glucose can be kept within the normal range. Roughly speaking, there are three degrees:
The degree of compensation shows how close glucose is to the target level. The target level itself (set using the HbA1c indicator) is determined by the physician for each patient individually, depending on age, coexisting conditions, and the risk of a sudden drop in blood sugar.
Sugar by itself does not directly “cause” diabetes. However, excess calories, including from sweets and sugary drinks, lead to weight gain and obesity, which is already one of the main risk factors. So there is a connection, but it is indirect: it is not about any single food, but about the overall balance of calories, weight, and activity.
General guidelines (the exact schedule is determined by the physician):
It is not the disease itself that is inherited, but a predisposition to it. If diabetes has occurred in close relatives, the risk roughly doubles, and if both parents were affected, it is even higher. But heredity is not destiny: weight control, healthy eating, and physical activity significantly reduce the chances that this predisposition will turn into the disease.
A complete discontinuation of medication cannot be guaranteed. In studies, some patients were able to reduce their dose of insulin or glucose-lowering medication after MSC therapy, but this is not the same as a full recovery. Any changes to the treatment regimen are made only by a physician based on test results; stopping medication on your own is dangerous.
The duration of the effect is individual and depends on the stage of the disease, lifestyle, and the body’s response. In many protocols, therapy is delivered as a course of several administrations, and repeat courses may follow. The effect is maintained only in combination with standard treatment and healthy habits; without them, it fades faster.
Find out which treatment will be effective in your case
Type 2 diabetes used to be considered a disease of adulthood, but in recent years it has increasingly been diagnosed in younger people, primarily because of the spread of obesity. The disease is closely linked to lifestyle: low physical activity, an unbalanced diet, and excess weight. However, reducing everything to habits alone would be inaccurate, as hereditary predisposition also plays an important role.
What causes type 2 diabetes? The disease usually develops where a hereditary predisposition is combined with an unhealthy lifestyle.
Risk factors fall into two groups.
Non-modifiable (cannot be changed):
Modifiable (can be changed):
Family history is one of the strongest factors: having diabetes in a father or mother roughly doubles the risk, and if both parents are affected, the risk rises even more. But heredity is not destiny: genes set the predisposition, while lifestyle determines whether it is realized.
Over time, elevated glucose levels damage blood vessel walls and nerve fibers. That is why type 2 diabetes is dangerous primarily because of its complications. The most common consequences of type 2 diabetes include:
Most of these complications develop over years and initially cause no symptoms. That is why regular monitoring of glucose, blood pressure, and weight, along with routine checkups, is important. They help slow the disease and detect changes at an early stage, when more can be done.
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